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Analyst Comment

Faron's new bexmarilimab patent extends product protection

By Antti SiltanenAnalyst
Faron Pharmaceuticals

Translation: Original published in Finnish on 8/11/2025 at 7:30 am EEST.

Faron announced on Friday that it has been granted a patent in the United States for the treatment of Clever-1 positive cancers with bexmarilimab and related structures. The decision extends the patent rights related to bexmarilimab to 2040. The original patent rights were valid until 2037 and were granted four years ago.

The new US patent covers the treatment of Clever-1 positive cancers with bexmarilimab and other constructs that bind to the Clever-1 molecule, producing the desired reprogramming effect. Faron's investigational drug bexmarilimab binds to the Clever-1 protein and inhibits its activity. The patent was granted based on a continuation application from the original composition of matter patent covering the structure of bexmarilimab. The original application included claims for both the substance and the treatment method. The newly granted patent covers the treatment of cancers that have Clever-1 positive cells in their microenvironment.

The news is naturally positive as the potential commercial period is extended, which increases the earnings potential of bexmarilimab. On the other hand, in its recently published investor presentation, the commercialization of bexmarilimab appears to be moving further into the future than our current assumptions. As new information, the company now estimates that accelerated marketing authorization in r/r MDS is possible in early 2028 (previously late 2026). Our model has assumed revenue starting in 2027. Patent and commercialization news balance each other out, and we will assess their significance more closely no later than in connection with the H1 report.

 

Faron is a global, clinical-stage biopharmaceutical company, focused on tackling cancers via novel immunotherapies. Its mission is to bring the promise of immunotherapy to a broader population by uncovering novel ways to control and harness the power of the immune system. The Company's lead asset is bexmarilimab, a novel anti-Clever-1 humanized antibody, with the potential to remove immunosuppression of cancers through reprogramming myeloid cell function. Bexmarilimab is being investigated in Phase I/II clinical trials as a potential therapy for patients with hematological cancers in combination with other standard treatments.

Read more on company page

Key Estimate Figures29/07

202425e26e
Revenue0.00.00.0
growth-%
EBIT (adj.)-18.7-18.9-30.5
EBIT-% (adj.)-466,750.0 %-472,000.0 %-762,390.0 %
EPS (adj.)-0.25-0.19-0.28
Dividend0.000.000.00
Dividend %
P/E (adj.)neg.neg.neg.
EV/EBITDAneg.neg.neg.

Forum discussions

Quote from Arvopaperi on 14.11.2024 “As Faron’s CEO, Jalkanen has given interviews in which he has outlined the company’s future development...
3 hours ago
by Kilohai80
13
It’s true that the clarification of funding is dragging on quite a bit. Regarding that statement from last May, the FDA really complicated things...
3 hours ago
by Mustonen Henri
5
10.5.2024 excerpt from Kauppalehti: ”Once phase 2 is completed and the FDA’s feedback determines the need for further investments, we can finalize...
3 hours ago
by Kilohai80
23
I’ll also add my own opinion that what happens virtually here regarding Faron doesn’t necessarily have anything to do with the waters Faron ...
3 hours ago
by Pekka
4
This is entirely a hallucination caused by investor fear and disappointment. Faron is not “dying” if a partnership or licensing agreement is...
4 hours ago
by OsakasOssi
12
Unfortunately, science has no value until supply and demand meet. How and when this deal happens then sets a baseline value for the company....
4 hours ago
by Jummijammi2
6
I think I commented on this same thing last time, but didn’t get a reply. When you looked at those other companies that have taken a loan from...
4 hours ago
by Johannes
19
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