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Press release

ExpreS2ion Biotechnologies: ExpreS2ion announces poster presentation on ES2B-C001 at the AACR Annual Meeting 2023

ExpreS2ion Biotech Holding

Hørsholm, Denmark, 18 April 2023 - ExpreS2ion Biotech Holding AB's affiliate ExpreS2ion Biotechnologies ApS ("ExpreS2ion") today announces that the company through its research collaboration partners at University of Bologna presented a poster on ES2B-C001, our unique HER2-VLP breast cancer vaccine candidate, at the American Association for Cancer Research (AACR) Annual Meeting, taking place April 14-19, 2023, in Orlando, Florida.

The presentation poster titled "Preclinical activity of ES2B-C001, a human candidate HER-2 virus-like particle (VLP) vaccine, against mammary carcinoma onset and metastasis" concludes, that:
  • ES2B-C001 vaccination inhibited the onset, growth, and metastatic spread of HER-2 positive mammary carcinomas in mice.

  • The vaccine induced strong and persistent antibody responses that inhibited human HER-2+ breast and gastric cancer cells in vitro.

  • ES2B-C001 is a promising candidate vaccine for the therapy of human tumours expressing HER-2. Preclinical results warrant further development towards human clinical studies.

A copy of the poster can be found at the company webpage (https://expres2ionbio.com/meet-us/) at https://expres2ionbio.com/meet-us/

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