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Press release

ExpreS2ion Biotechnologies: Scientific article published about the Phase I clinical trial of the COVID-19 vaccine ABNCoV2

ExpreS2ion Biotech Holding

Hørsholm, Denmark, January 20, 2023 - ExpreS2ion Biotech Holding AB's affiliate ExpreS2ion Biotechnologies ApS ("ExpreS2ion") announces that the journal The Lancet Microbe published an article about the COVID-19 vaccine candidate ABNCoV2 titled "First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2" co-authored by ExpreS2ion scientists.

Abstract excerpt: "Immunisation with ABNCoV2 was well tolerated, safe, and resulted in a functional immune response. The data support the need for additional clinical development of ABNCoV2 as a second-generation SARS-CoV-2 vaccine. The modular cVLP platform will accelerate vaccine development, beyond SARS-CoV-2."

This publication is a result of the close research collaboration in the COUGH-1 trial study group under the Prevent-nCoV consortium as announced in August 2021 (https://news.cision.com/expres2ion-biotechnologies/r/positive-safety-and-efficacy-outcome-of-the-covid-19-clinical-phase-i-ii-study-for-the-abncov2-vacci,c3393447) and November 2021 (https://news.cision.com/expres2ion-biotechnologies/r/further-efficacy-data-from-the-covid-19-clinical-phase-i-ii-study-with-abncov2-confirms-strong-posit,c3451644).

The scientific article reference: Merel J Smit; Adam F Sander; Maud B P A Ariaans; Cyrielle Fougeroux; Constanze Heinzel; Rolf Fendel; Meral Esen; Peter G Kremsner; Rob ter Heine; Heiman F Wertheim; Manja Idorn; Søren Riis Paludan; Alexander P Underwood; Alekxander Binderup; Santseharay Ramirez; Jens Bukh; Max Soegaard; Sayit M Erdogan; Tobias Gustavsson; Stine Clemmensen; Thor G Theander; Ali Salanti; Mette Hamborg; Willem A de Jongh; Matthew B B McCall; Morten A Nielsen; Benjamin G Mordmüller; Robert Dagil; Louise Goksøyr; Thomas M Hulen; Christoph Janitzek; Daniel S Jensen; Sune Justesen; Paul K Khalifé; Andrea Kreidenweiss; Telma Lança; Olivia Lie-Andersen; Karina Teelen; Elena Vidal-Calvo. First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2. The Lancet Microbe. 2023 - https://doi.org/10.1016/S2666-5247(22)00337-8. The article can also be found via this link (https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00337-8/fulltext), as well as via the Research Publications (https://expres2ionbio.com/newspublications/research-publications/) page of ExpreS[2]ion's website.  

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